(Intermetatarsal Neuroma)

Morton’s neuroma is a thickening of nerve tissue between the toes. It commonly affects the nerve that travels between the third and fourth toes.

Nonsurgical treatment does not always improve symptoms. Surgery may be necessary if the symptoms do not improve with conservative treatment.


  • Tingling in the space between the third and fourth toes
  • Toe cramping Sharp, shooting, or burning pains in the ball of your foot (and sometimes toes)
  • Pain that increases when wearing shoes or pressing on the area
  • Pain that gets worse over time


Orthotics and corticosteroid injections are widely used to treat Morton’s neuroma. If such interventions fail, patients are commonly offered surgery known as neurectomy which involves removing the affected piece of nerve tissue.

A foot x-ray may be done to rule out bone problems.

MRI or high-resolution ultrasound can successfully diagnose Morton’s neuroma.

Nerve testing (electromyography) cannot definitely diagnose Morton’s neuroma, but may be used to rule out conditions that cause similar symptoms.

Your doctor may order blood tests to check for inflammation-related conditions, including certain forms of arthritis